中國藥理學(xué)與毒理學(xué)雜志(2017年05期)
Chinese Journal of Pharmacology and Toxicology

目 錄

• 苯并(a)芘致癌的表觀遺傳學(xué)作用機(jī)制研究進(jìn)展
• 積雪草苷對(duì)低氧肺動(dòng)脈高壓中內(nèi)皮-間充質(zhì)轉(zhuǎn)化的作用（英文）
• 歡迎訂閱2017年《中國藥理學(xué)與毒理學(xué)雜志》
• 姬松茸多糖ABP-AW1對(duì)免疫功能低下小鼠的免疫增強(qiáng)作用
• 中國毒理學(xué)會(huì)第八次全國毒理學(xué)大會(huì)暨第七屆全國會(huì)員代表大會(huì)第一輪通知
• 酸棗仁皂苷A對(duì)糖尿病模型大鼠腎小球細(xì)胞凋亡的影響
• 吡唑啉酮衍生物鎘(Ⅱ)配合物體內(nèi)外對(duì)黑素瘤B16細(xì)胞的抗腫瘤作用
• 芫花素對(duì)模式生物秀麗隱桿線蟲的毒性作用
• 2016年第二屆藥物代謝朝陽論壇在廈門成功舉辦
• 二乙烯砜-谷胱甘肽系列加合物的制備及其與體外DNA加合反應(yīng)活性
• 秀麗隱桿線蟲衰老與衰老相關(guān)神經(jīng)退行性疾病模型及藥物篩選研究進(jìn)展
• GATA1轉(zhuǎn)錄因子調(diào)控巨核細(xì)胞分化機(jī)制的研究進(jìn)展
• 用磷酸化蛋白組學(xué)分析鑒別磷酸二酯酶功能（英文）
• 4-型磷酸二酯酶與局部cAMP信號(hào)調(diào)節(jié)（英文）
• 機(jī)械熱痛覺感受器的熱痛感受機(jī)制（英文）
• 環(huán)核苷酸磷酸二酯酶:神經(jīng)精神疾病的藥物作用靶標(biāo)（英文）
• 星形膠質(zhì)細(xì)胞Drd2受體通過β-arrestin2抑制NLRP3炎癥小體活化
• 抑郁癥發(fā)病機(jī)制研究的新視角:谷氨酸受體膜穩(wěn)定性及其調(diào)控（英文）
• 顳葉癲癇異常神經(jīng)環(huán)路分析（英文）
• Phosphodiesterase 1:a unique therapeutic target with multiple potential indications
• Targeting phosphodiesterases for cognition enhancement:a translational approach
• Phosphodiesterases:novel targets for treatment of alcoholism
• PDE10A inhibitor in addiction
• Regulation and function of cyclic nucleotide phosphodiesterases in pathological vascular remodeling
• Role of PDE4D splice variants in the mediation of antidepressant and cognition-enhancing actions and its mechanisms
• Mitochondrial dynamics as a therapeutic target for Alzheimer disease
• 新型抗阿爾茨海默病藥物甘露寡糖二酸
• LW-AFC,a new traditional Chinese medicine formula,shows promising therapeutic effects on Alzheimer disease
• A novel mechanism underlying the protective effect of PDE4 inhibitor against cognitive impairment:inhibiting neuroinflammation through inducing autophagy in microglial cells
• Loss of microglial autophagy causes Parkinson disease-like symptom in mice
• Modulation of abnormal neuronal circuit in temporal lobe epilepsy
• The decrease of connexin43 mediated down-regulation of glutamate transporter1 in spinal astrocytes under inflammatory condition
• Gngerol in the improvement of Aβ-induced learning and memory impairment
• Protective effects of Radix Cynanchum bungei on ischemia-induced neuronal and cognitive impairment in mice
• 基于NLRP3炎性小體通路研究葡萄籽原花青素對(duì)AD大鼠的保護(hù)作用
• Protective effects of betaine on ischemia-reperfusion injury through ROS pathway in rat
• Role of endothelial receptor-tyrosine kinase ErbB4 in regulating brain function
• Neuroprotective effect of isoliquriitin on corticosterone-induced apoptosis in PC12 cells
• A review of studies on neuroprotective aspects of bioactive polysaccharides
• Application of nanoparticles modified with angiopep-2 in the diagnosis and treatment of glioma
• Protective effects of resveratrol nanosuspensions loaded in situ hydrogel on Alzheimer disease model mice after intranasal administration
• 生物堿類磷酸二酯酶抑制劑治療帕金森疾病可行性探討
• Genetically engineered systems revealed the roles of basal ganglia in sleep-wake regulation
• In the dorsal raphe neucleus,the role of Ca~(2+),PKC and CaMKⅡ in sleep-wake regulation
• 面向航天特因環(huán)境認(rèn)知損傷及防護(hù)的動(dòng)物行為實(shí)驗(yàn)技術(shù)
• EphB4信號(hào)通路對(duì)人胚胎神經(jīng)干細(xì)胞自我更新、增殖、分化和凋亡的影響
• Preparation and evaluation of silymarin nanosuspensions for protective effects on stress-induced liver injury
• 快速起效抗抑郁-焦慮的靶標(biāo)策略與新藥研究
• 記憶網(wǎng)絡(luò)中的N-甲基-D-天冬氨酸受體
• 抑制星形膠質(zhì)細(xì)胞Hsp90-GLT1的抗癲癇機(jī)制研究
• Disturbance of cholinergic Grb2-associated-binding protein 1 signaling participate in the pathological process of cognitive dysfunction
• Effects of ketamine on mouse hippocampal inflammatory cytokines IL-6,IL-1β and TNF-α levels in acute and chronic administration models
• A network pharmacology approach to decipher the mechanisms of anti-depression of Xiaoyaosan formula
• Baicalin treatment regulates hyperactivity of HPA axis and alters SIRT1 related inflammation in the hypothalamus in a model of depression
• BDNF dependent Rac1 GTPase activation in the vmPFC contributes to aversive memory extinction by Arc-mediated GABAA receptor endocytosis
• Attenuation of opioid addiction in mice lacking aquaporin 4
• Brucine N-oxide reduces ethanol intake and preference in alcohol-preferring Fawn-Hooded rats
• 新型磷酸二酯酶特異性抑制劑的發(fā)現(xiàn)及識(shí)別機(jī)制
• Protective effects of puerarin on alcohol-induced oxidative injury in PC12 cells
• Protective effect of gingerol dropping pills against alcoholic liver injury in mice
• Overexpression of SIRT6 prevents hypoxia-induced apoptosis in osteoblast cells
• 蘆薈多糖對(duì)實(shí)驗(yàn)性口腔潰瘍大鼠NF-κB和MMP2表達(dá)的影響
• Screening of active ingredients of Taohong Siwu Decoction on platelet membrane receptor
• 丹參酮ⅡA對(duì)心血管系統(tǒng)的藥理作用及其新劑型研究進(jìn)展
• 荷葉堿在大鼠體內(nèi)的吸收、分布、代謝和排泄研究
• 抗壞血酸插層鐵鋯復(fù)合氧化物的制備及緩釋性能評(píng)價(jià)
• 芍藥苷對(duì)異丙腎上腺素誘導(dǎo)大鼠心肌重構(gòu)的干預(yù)作用
• Primary culture and identify of cerebral cortical astrocytes from Sprague-Dawley rats
• Effect and mechanism of persimmon leaf flavonoid treatment of experimental oral ulcer
• 玉米須水提物對(duì)自發(fā)性高血壓大鼠血小板聚集功能的影響
• 玉米須水提物對(duì)自發(fā)性高血壓大鼠的降壓作用
• 作者索引
• 書訊