沈陽藥科大學學報(2008年S1期)
Journal of Shenyang Pharmaceutical University

目 錄

• Pharmacogenetics of response to simvastatin in Chinese patients with hyperlipidaemia
• Effects of ginsenosides on vascular reactivity in rat cerebral and renal arteries
• Cathelicidin stimulates colonic mucus synthesis by up-regulating MUC1 and MUC2 expression through a mitogen-activated protein kinase pathway
• Interactions between neuronal and non-neuronal cells in adult rat isolated dorsal root ganglion cells
• An essential role of endothelium-derived nitric oxide in vasorelaxations induced by black tea polyphenols
• Astragalus saponins induce apoptosis in human gastric adenocarcinoma cells via a caspase 3-dependent pathway
• Endothelial dysfunction:EDCF revisited
• Salvianolic acid B protects endothelial cells from oxidant-mediated damage
• Cardiac protection of new compounds from scientific Chinese medicine (SCM)
• Investigation on novel pharmacological target against pulmonary hypertension
• The mechanism of BRCA1 participate sporadic breast carcinomas genesis
• Effects of resveratrol,curcumin and their derivatives on the activation of microglia induced by LPS
• Anti-tumor effects of VnA in in vitro cultured Colon26-L5 cells and in vivo Colon26-L5 cells planted mice
• Specification of phase Ⅰ of new drugs‘ clinical tolerance trials
• Approach for mechanism of BH3 domain counterpart BH3I-2‘ inducing colorectal cancer cell apoptosis
• Experience of clinical pharmaceutical care carried out in pediatric respiratory department
• 甲基苯丙胺神經毒性,成癮機制及其濫用防治研究進展
• 免疫調節(jié)相關的信號轉導通路研究現狀
• 阿爾茨海默病動物模型研究進展
• 葡萄籽提取物化學成分及藥理活性的研究進展
• Synaptotagmin Ⅶ研究進展
• β淀粉樣蛋白在阿爾茨海默病病因學中作用研究進展
• BRCA1基因突變及啟動子甲基化與乳腺癌
• 白藜蘆醇的藥理學作用研究進展
• Pranlukast dose-and time-dependently protects against ischemic neuronal damage in the rat hippocampus
• Effects of acute and chronic administration of MK-801 on c-Fos protein expression in mice brain regions implicated in schizophrenia and antagonistic action of clozapine
• Targeted to medication-induced dyskinesia and tardive dyskinesia:A role of 5-HT_(1A) receptor
• Anti-free radical and cytoprotective effects of quercetin and its sugar-containing natural congeners in cultured HEK293 cells injured by anoxia/hypoglycemia and the structure-effect relationship thereto
• Rosiglitazone prevents gliosis,oxidative/nitrative stress and memory deficits induced by intracerebroventricular injection of streptozotocin in rats
• The regulation of agmatine on MMP expression in the cerebral endothelial cells overexpressed ADC gene
• (-)表沒食子兒茶素沒食子酸酯在D-半乳糖所致癡呆小鼠體內的抗氧化作用
• 維生素E對阿爾茨海默病模型鼠學習記憶能力的影響
• 慢性鋁暴露對成年大鼠海馬LTP及谷氨酸含量的影響
• EGCG對D-半乳糖誘導的阿爾茨海默病小鼠的抗凋亡作用
• Effects of Xanthoceraside on learning and memory impairment in mice induced by i.c.v.Aβ_(1-42)
• Protective effect of Xanthoceraside on injuried PC12 cells in vitro
• Effects of the ephedra alkaloid methylephedrine on the basal evoked potential transportation and the long-term potentiation (LTP) in the rat hippocampal dentate granule cells in vivo
• FANCF基因沉默對人乳腺癌細胞生物學特性的影響
• BRCA1和相關蛋白在乳腺癌中的表達與相關分析
• 在不同亞群的散發(fā)性乳腺癌組織中BRCA1蛋白的表達
• HER-2/neu基因沉默對子宮內膜癌細胞株Ishikawa細胞增殖及其對孕激素敏感性的影響
• APC、SMAD4雙基因沉默研究WNT通路、TGF-β通路對大腸癌細胞粘附作用的交叉調控機制
• 不同散發(fā)性乳腺癌群體的BRCA1和CEP17基因拷貝數
• Research of BH3 domain protein inducing cell apoptosis
• Study on HepG-2 apoptosis induced by saponins isolated from Asparagus and the effects on the activities of caspase-3,8,9
• The new research on mitochondria
• Advance research in apoptosis mediating by death receptor
• Effect of Juglone in qinglongyi on cell cycle status and apoptosis in A-549 cells
• Effect of Asparagus polysaccharide on the number and activity of erythrocyte complement receptor 1 (CD35) of S_(180) mice
• Effect on apoptosis、mitochondrial membrane potential and Ca~(2+) concentration in HepG-2 by CSEO
• The progress of study on pathogenesis in ovarian cancer
• Development of survivin and tumor research
• Studies of pancreatic carcinogenesis
• The new research on tumor suppressor gene in hepatocellular carcinoma
• Study on inhibitory effect by total alkaloids in Capparis spinosa on SGC-7901 in vitro
• Initial study on apoptosis in HepG-2 Human heptocarcinoma cell line by CSS
• Study on preliminary mechanism of apoptosis in HepG-2 by CSA
• Induction of apoptosis by furanodiene in HL60 leukemia cells through activation of TNFR1 signaling pathway
• Cucurbitacin E inhibits the proliferation of hepatoma cells in vitro and in vivo through induction of G2/M phase arrest
• 2(±)-7,8,3‘,4‘,5‘-Pentamethoxyflavan induces G2/M phase arrest and apoptosis in human leukemia HL60 cells
• Study on anti-hepatocarcinoma activity of tectorigenin from Pueraria Flos in vitro
• The effects of multidrug resistance protein 2 (Mrp2) and breast cancer resistance protein (Bcrp) on biliary excretion of cefditoren in rats
• HFI對卵巢癌裸鼠移植瘤的療效
• 中國散發(fā)性乳腺癌中ERα表達與ERα基因啟動子甲基化相關性研究
• Cytoprotective effects of quercetin and its sugar-containing natural congeners in cultured HEK293 cells injured by anoxia/hypoglycemia and the structure-effect relationship thereto
• Signal transduction mediated by mitogen-activated protein kinases and apoptisis of tumor cells
• Investigation of anticancer effect of Xanthoceraside in vitro and the mechanism of Xanthoceraside-induced human breast cancer MCF-7 cell death
• Influence of SLYWG on malignant tumor ascites
• Time-dependent study of combined chemotherapy of Cyclophophamide,Cisplatin and Adriamycin
• Diallyl trisulfide activates NADPH oxidase by inducing the expression of NADPH oxidase subunits and translocation of both Rac2 and p67phox subunit in HL-60 cells
• The production and cytotoxicity of the reactive oxygen species (ROS) induced by diallyl trisulfide (DATS) in human myeloid leukemia HL-60 cells
• The effects and mechanisms of cytoplasmic Macrophage colony-stimulating factor (M-CSF) on the proliferation,migration and invasion of HeLa cells
• Effect of the interaction between M-CSF and MCM7 on DNA replication in HeLa cells
• 蛋白酶體抑制劑MG132對胃癌細胞系AGS和SNU484增殖的影響
• 葡萄籽提取物F3對U87細胞抗腫瘤、趨化作用及機制探討
• 姜黃素衍生物對人白血病細胞株HL-60增殖的抑制作用及初步機制探討
• 葡萄籽提取物F2對人惡性膠質瘤U-87細胞的抑制增殖作用及對其甲酰肽受體(FPR)功能的影響
• Antithrombotic efficacy of MV1 serine protease in a canine model of unstable angina
• Increased plasma levels of Lp(a) enhance the development of coronary atherosclerosis
• 糖尿病大鼠心肌鈉鈣交換蛋白與肌漿網鈣泵mRNA表達水平的研究
• Inhibitory effects of Veratrum nigrum L. Var. ussurience Nakai alkaloids on the hypertrophy of cardiomyocytes from neonatal rat
• Study on effect and mechanism of Celastrus Orbiculatus total terpenoids in regulating lipid metabolism
• Influence of styptic fiber on clotting time in rabbits
• Primary study of muscone‘s effect on cardiovascular system
• (-)-Stepholodine induced enhancement of cardiac muscle contractions mediated by D_1 receptors
• The roles and relations of calpastatin,calmodulin and an undefined cytoplasmic factor in the regulation of cardiac L-type Ca~(2+) channels
• The pharmacodynamics experiment of Xinkang injection protect action of ADR-induced toxin myocarditisin mice
• Maternal endotoxemia results in increases in blood pressure and body weight in rats
• Targeting at SUR2B/Kir6.1 subtype of ATP-sensitive potassium channel opener natakalim improves pressure overload-induced heart failure
• 健康中國男性志愿者單劑量口服10mg鹽酸美金剛膠囊及片劑的藥代動力學及生物等效性比較研究
• Pharmacokinetics and bioavailability of R-phencynonate in Beagle dogs
• Pharmacokinetics study of extended release formulations of buspirone hydrochloride in Beagle dogs
• A reversed-phase HPLC-UV assay for simultaneous analysis of EGCG and ECG of tea polyphenols in rat plasma
• Determination of JBP485 by LC/MS and its pharmacokinetics in rats
• Study on the pharmacokinetics of tea polyphenols injection in rat plasma
• Comparison of pharmacokinetics of Alprazolam after intranasal and intragastric administration in rats
• Involvement of CYP2B6 in the biotransformation of propofol by human liver microsomes
• The study of bioavailability and bioequivalence of oseltamivir in Chinese health volunteers
• The effect of Asparagus officinalis polysaccharide on erythrocyte of S_(180) mice played in immunological reaction of lymphocytes
• The total flavonoids extracted from Xiaobuxin Tang reverse the hyperactivity of hypothalamic-pituitary-adrenal axis in chronically stressed rats
• Salvianic acid A inhibits induction of inflammatory mediators by blocking Nuclear Factor-κB activation in macrophages
• Experimental studies on antipyretic,analgesic and antibacterial effects of GK 001,a poly-prescription of traditional chinese medicine
• Relaxant effect of an estrone derivate EA303 on isolated colonic smooth muscle of rabbits
• 卡介菌多糖-核酸對二硝基氟苯誘導的接觸性皮炎的治療作用及機制
• 卡介菌多糖-核酸抗Ⅰ型過敏反應作用及機制探討
• 哮喘大鼠肺泡巨噬細胞IL-6及TNF-α的表達水平及其意義
• Scopolin isolated from Erycibe obtusifolia Benth stems suppresses adjuvant-induced rat arthritis by inhibiting inflammation and angiogenesis
• Effect of Xiaofenghuoxue decotion on Th1 and Th2 cytokine production in BALF in allergen-induced asthma guinea pigs
• Ginsenoside metabolite IH 901 reduced foam cell formation in vitro
• Study on mechanisms of hypertension in rat adult offspring following prenatal exposure to immuno-inflammatory stimulants
• Preliminary molecular basis of Danggui-buxue-tang on Qi deficiency and blood stasis syndrome
• Influence of astragaloside on gastric mucosa of stress ulcer rats
• Genome-wide identification of gene expression in the epididymis of infertile rat induced by alpha-chlorohydrin using oligonucleotide microarray
• 鉀通道在維拉帕米抑制上皮鈉通道中的作用
• The effect of Sachalin rhodiola rhizome extract on liver starch and liver cell morphous of sports fatigue rat
• Effect of Tanshitone on prevention and treatment of retinoic acid-induced osteoporosis in mice
• The effects and mechanisms of Gushudan against osteoporosis
• Comparative study on pharmacokinetics of Cephradine in diabetic and normal rats
• 環(huán)磷酰胺介導小鼠骨髓抑制動物模型的建立
• Research on pharmacological mechanism of the treatment of Asthma by oral Bordetella pertussis
• Extraction and separation of total flavonoids from Flos Puerariae and its antioxidant activity
• Study of inducibility and mechanism of phase 2 enzymes by quercetin and rutin
• The protecting effects and mechanism of betaine hydrochloride on hepatic ischemia-reperfusion injury in rats
• 哮喘大鼠肺泡巨噬細胞電壓依賴性鉀通道的活性變化
• Distribution and excretion of N-Ile1 Thr2-63-desulfatohirudin in rats
• Modernization of Chinese herbal compound and the high performance liquid chromatography tandem mass spectrometry (HPLC-MS)
• Study on pharmacodynamics of recombinant interferon α-2b suppository
• The rat bowel of β-asaron absorbs the research
• 早期糖尿病大鼠背根神經節(jié)以及主動脈中COX-2 mRNA和血中PGE_2的變化
• 人體血漿中尼莫地平的檢測
• Effects of two novel sugar drug candidates on CYP450 isoforms in different sexed Chinese human liver microsome in vitro
• Transforming Growth Factor-beta signal responding in hepatic stem-like cells
• Anti-diarrheal and spasmolytic activities study of 3,4-Dihydro-2-(4-Morpholinylmethy)-1(2H)-Naphthalenone(CY)
• The relationship between antimicrobial consumption and the rates of resistance of Klebsiela pneumoniae in respiratory unit
• Anti-osteoporosis effect of the standard extract of Pueraria Lobata
• Effect of Bixieqianggupian on experimental osteoporosis in rats
• Effect of Ginsenoside Re on shock
• Effect of matrine hydrochloride on liver injury
• Effect of melatonin on endogenous circadian rhythm
• Effect of the Ginseng extractive E on experimental climacteric disturbance in rats
• Relaxation effects of matrine on guinea-pig aortic smooth muscles
• Effect of Pesticides on soil microbial and enzyme activity
• Gene cloning,expression analysis of JcACP (Acyl Carrier Protein) in Jatropha curcas L. and its prokaryotical expression
• Preparation and characterization of solid dispersions of Quercetin with PEG4000
• Effects of melatonin on pethidine-induced physical dependence and its antioxidative action
• The molecular mechanisms of the analgesic action of melatonin
• Effects of Charred Fructus Crataegi on the contractilily of isolated rat gastric and intestine muscle strips
• 褪黑素與油酰胺聯合應用后大鼠催眠作用的變化
• RC的抗應激作用及其機制初探
• 海星醇提取物對胃腸動力影響的研究及機制初探
• 純鎂及鎂合金材料用于骨組織工程的初步研究
• 氣相色譜法測定人血漿中卵磷脂絡合碘的濃度
• 應用膏狀固體酒精灼燒法建立一種新的大鼠燒傷模型
• 一種新的重組蝎抗神經興奮肽對原代培養(yǎng)的大鼠海馬神經元鈉電流的影響
• 原花青素對乙醇引起的神經元抗壞血酸釋放的影響