AbouttheCover
摘要: Manytumor-relatedgenemutationsoccurinthecodingregions,whichoftenresultinsingle-pointaminoacidresiduealternationoncorrespondingproteins.Thesemutationsmay,todifferentextents,causemalfunctionofagivenproteinbyaffectingitsfolding,enzymaticactivityorintermolecularinteraction.Itispossibletopredicttheconsequencesofthesetumor-associatedmutationsbyanalyzingthestructure ...
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