Pharmacological action and mechanisms of ginkgolide B

摘要： <正> Objective To review the recent research progress in pharmacological actions and mechanisms of ginkgolide B.Data sources Information included in this article was identified by searching of PUBMED (1987-2006) online resourcesusing the key terms "ginkgolide B","platelet activating factor",and "pharmacological".Study selection Mainly original milestone articles and critical reviews written by major pioneer investigators of the fieldwere selected.Results The key issues related to the pharmacological actions and mechanisms of ginkgolide B were summarized.Theginkgolide B possesses a number of beneficial effects such as anti-inflammatory,anti-allergic,antioxidant,andneuroprotective effects.Meantime,their mechaniams were discussed.Conclusions The Ginkgolide B is the most potent antagonist of platelet activating factor (PAF) and exhibits therapeuticaction in a variety of diseases mainly by the PAF receptor. ... （共7頁）