Oxidant/antioxidantbalanceintheaqueoushumorofpatientswithglaucoma
摘要: AIM:Toevaluatetotalantioxidantstatus(TAS),totaloxidantstatus(TOS),andtheoxidativestressindex(OSI)oftheaqueoushumor(AH)inpatientswithglaucoma.·METHODS:Theprospectivestudywascomposedofastudygroup(n=31)andacontrolgroup(n=31).Fifteenpatientsinthestudygroupwerediagnosedwithprimaryopenangleglaucoma(POAG),and16patientswerediagnosedwithpseudoexfoliationglaucoma(PEG).Thecontrolgroupwascomposedofnon-glaucomatouspatientswithcataracts.AHsampleswerecollectedandanalyzedforTAS,TOS,andOSIlevels.·RESULTS:MeanAHTASlevelwassignificantlyhigherinpatientswithglaucomathanthatinthecontrolgroup(P<0.01).MeanTOSandOSIlevelstendedtoincreaseinpatientswithglaucoma.NosignificantdifferencesinTAS,TOS,orOSIlevelswereobservedbetweenpatientswithPOAGandPEG.·CONCLUSION:HighlevelsofTASwereobservedinpatientswithglaucoma,whichwaslikelyaresponsetotheincreasedoxidativestressobservedinthesepatients. ...
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